I think not!
In Mind in Life, chapter on Autopoiesis and Teleology, Evan Thompson distinguishes between extrinsic and immanent purposiveness. He writes that Maturana and Varela’s original antiteleological stance was directed against the former — the functionalist idea that purpose is attributed by an observer situating a system in some larger context. But this leaves immanent purposiveness entirely untouched. In an autopoietic system, every part produces and is produced by the whole, meaning causal relations are simultaneously means-end relations. Purposiveness here is neither imposed from outside nor a mysterious internal essence — it’s a constitutive property of the system’s organisation as a whole. It is intrincially purposive in pursuit of survival.
Thompson also shows that Varela himself eventually abandoned the anti-teleological position. In a late essay with Andreas Weber, he argued that autopoiesis entails immanent purposiveness in two complementary modes: identity, the maintenance of a dynamic self through material change, and sense-making, the organism’s active orientation toward its environment. And sense-making, Varela explicitly argues, is intentionality in its minimal and original biological form. So the claim that phenomenology and enactivism support a merely “apparent” reading of purpose is not just contestable — it runs directly counter to where Varela himself ended up.
From Mind in Life: Biology, Consciousness, and the Phenomenology of Life, Evan Thompson
In Phenomenology of Biology, Appendix 1 to the First Essay, Hans Jonas argues as follows. Hume showed that causation isn’t found among percepts — ‘This is incontrovertible so long as “perception” is understood, with Hume, as mere receptivity that registers the incoming data of sensation’ . But, he says, the “decausalized” world of observation isn’t really givn; it’s an abstraction . The apparent priority of stable, enduring entities over dynamic activity underwrites the mechanistic worldview.
(The) result: the apparent priority of enduring entity over occasional activity— the cognitive child of perception — is an inversion of the originative ontological order, and the root of a theoretical problem of causality later on.
The positive source of causal knowledge, which both Hume and Kant neglect, is bodily action — what Jonas calls “animal nisus,” the direct experience of force exerted and resisted. And this is one of the original statements of ‘enactivism’! Bodily action is not inferred or constructed; it is originally experienced from within. The body, not perception, is where we actually encounter causality as such (reminiscent of Schopenhauer).
The connection to the OP is that the “meaningless universe” isn’t discovered by science, it’s produced by the objectifying stance that perception and then theory impose on experience. Jonas gives the genetic account of how that abstraction arises and what it costs. And crucially, the suppression of force, agency, and purpose from the theoretical picture doesn’t mean they aren’t real — it means the theoretical picture has systematically excluded them as the condition of its own possibility - just as the OP says.
On page 80, Jonas provides a luminous interpretation of hylomorphism:
Let us consider further this new element of freedom that appears in organism , with special reference to form. Form, we h ave seen, is an essential and a real, that is, efficacious, characteristic of life. It is only with life that the difference of matter and fo rm , in respect to lifeless things an abstract distinction, emerges as a concrete reality. And the ontological relationship is reversed: form becomes the essence, matter the accident. In the realm of the lifeless, form is no more than a changing composite state, an accident, of enduring matter. And viewed from the fixed identities of the changing material contents, as the inventory of each moment would record them, the living form too is only a region of local and temporal transit in their own movements, its apparent unity passing, configurative state of their multiplicity. But viewed from the dynamic identity of the living form, the reverse holds : the changing material contents are states of its enduring identity, their multiplicity marking the range of its effective unity. In fact, instead of saying that the living form is a region of transit for matter, it would be truer to say that the material contents in their succession are phases of transit for the self continution of the form.
Throughout Jonas, he stresses the ‘needful freedom’ of the organism. For Jonas, the organism is paradoxically both free and needful — and the two are inseparable. It’s free in the sense that it has achieved a kind of independence from any particular parcel of matter; it maintains its identity through continuous material exchange, which no mere physical thing does. But that very freedom is purchased at a cost: precisely because the organism is not identical with its material contents, it depends on a constant supply of new matter and energy to sustain itself. It must keep going, or cease to be. It has, in Jonas’s phrase, a need to be.
This is what separates even the simplest organism from a stone. The stone is indifferent to its own continuation — nothing is at stake in its persistence or dissolution. The organism, by contrast, is always teetering between being and non-being, and its entire activity is oriented toward maintaining itself on the right side of that threshold. That orientation — however unconscious, however minimal — is what Jonas means by concern, and it’s what makes the organism a subject of a kind, however rudimentary, rather than merely an object.
The Phenomenon of Life: Toward a Philosophical Biology, Hans Jonas